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Article

Selection of hepatitis B virus polymerase mutations in HIV-coinfected patients treated with tenofovir.

Antiviral therapy - 1 Jan 2005

Sheldon Julie, Camino Nuria, Rodés Berta, Bartholomeusz Angeline, Kuiper Michael, Tacke Frank, Núñez Marina, Mauss Stefan, Lutz Thomas, Klausen Gerd, Locarnini Stephen, Soriano Vincent

Abstract excerpt

BACKGROUND: Tenofovir (TDF) is an adenosine nucleotide analogue that has been approved for the treatment of HIV-1 infection. It also shows activity against hepatitis B virus (HBV) in patients with or without lamivudine (LAM)-associated mutations. Development of clinical or virological HBV breakthrough during TDF therapy has not been reported so far. The aim of this study was to analyse the HBV polymerase (pol)...

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PMID: 16218172

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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