Article
Tenofovir is effective alone or with emtricitabine in adefovir-treated patients with chronic-hepatitis B virus infection.
Gastroenterology - 1 Oct 2010
Berg Thomas, Marcellin Patrick, Zoulim Fabien, Moller Bernd, Trinh Huy, Chan Sing, Suarez Emilio, Lavocat Fabien, Snow-Lampart Andrea, Frederick David, Sorbel Jeff, Borroto-Esoda Katyna, Oldach David, Rousseau Franck
Abstract excerpt
BACKGROUND & AIMS: We compared treatments for patients with chronic hepatitis B virus (HBV) infection who had an incomplete response to adefovir dipivoxil (ADV). We evaluated a combination of fixed-dose emtricitabine (FTC) and tenofovir disoproxil fumarate (TDF) from the start (early combination) versus TDF as monotherapy. METHODS: Patients (n = 105) were randomly assigned to groups given TDF (n = 53) or FTC/TDF...
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