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Tenofovir for patients with lamivudine-resistant hepatitis B virus (HBV) infection and high HBV DNA level during adefovir therapy.

Hepatology (Baltimore, Md.) - 1 Aug 2006

van Bömmel Florian, Zöllner Bernhard, Sarrazin Christoph, Spengler Ulrich, Hüppe Dietrich, Möller Bernd, Feucht Heinz-Hubert, Wiedenmann Bertram, Berg Thomas

Abstract excerpt

Incomplete virological response to adefovir dipivoxil (ADV) has been observed in patients with lamivudine-resistant hepatitis B virus (HBV) infection and may be associated with developing resistance and disease progression. We therefore investigated whether the efficacy of viral suppression could be improved by replacing ADV with tenofovir disoproxil fumarate (TDF). Twenty patients with chronic HBV infection (18...

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PMID: 16871563
DOI: 10.1002/hep.21253

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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