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Article

Genetic variability in the NMDA-dependent AMPA trafficking cascade is associated with alcohol dependence.

Addiction biology - 1 Jul 2012

Karpyak Victor M, Geske Jennifer R, Colby Colin L, Mrazek David A, Biernacka Joanna M

Abstract excerpt

Model studies in mice indicate that the severity of alcohol withdrawal is associated with polymorphic variation and expression of the MPDZ gene. Current knowledge about variation in the human MPDZ gene is limited; however, our data indicate its potential association with alcohol dependence. The multi-PDZ protein is an important part of the N-methyl-D-aspartate (NMDA)-dependent...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21762291
DOI: 10.1111/j.1369-1600.2011.00338.x
PMCID: PMC3197973

Genes

MPDZ

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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