Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The plasma concentration of activated protein C appears normal in patients with haemophilia.

Haemophilia : the official journal of the World Federation of Hemophilia - 1 Mar 2009

Schulman S, Eelde A, Blombäck M, Stenflo J

Abstract excerpt

Increased concentration of activated protein C (APC) has been observed in patients with thromboembolic disorders, but whether the level of APC in patients with bleeding disorders is decreased remains unknown. Seventy patients with haemophilia A or B with mild, moderate or severe form were studied. Detailed information on bleeding, arthropathy and factor consumption was collected during a 10-year period. The...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Analysis of Variance
Share to Biomarkers
Share to Enzyme Activation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hemophilia A

Share to Hemophilia B

Share to Predictive Value of Tests

Share to Protein C

Share to Thrombin

Source

Identifiers

PMID: 19175419
DOI: 10.1111/j.1365-2516.2008.01957.x

Genes

APC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The plasma concentration of activated protein C appears normal in patients with haemophilia.PMID 19175419Read ↗

Low level of circulating activated protein C is a risk factor for venous thromboembolism.Semantic proximity Read ↗

The structure-function relationship of activated protein C. Lessons from natural and engineered mutations.Semantic proximity Read ↗

Endothelium-Dependent Protein C Activation in Hereditary Protein C Deficiency.Semantic proximity Read ↗

No effect of the prothrombin G20210A mutation on protein C activation in a large kindred with type I protein C deficiency.Semantic proximity Read ↗

APC resistance: biological basis and acquired influences.Semantic proximity Read ↗

Platelet degranulation and glycoprotein IIbIIIa opening are not related to bleeding phenotype in severe haemophilia A patients.Semantic proximity Read ↗

Influence of factor VIII/von Willebrand complex on the activated protein C-resistance phenotype and on the risk for venous thromboembolism in heterozygous carriers of the factor V Leiden mutation.Semantic proximity Read ↗

Resistance to activated protein C and low levels of protein S activity in nine thrombophilic families: a correct diagnosis.Semantic proximity Read ↗

Effects of oral anticoagulant therapy and haplotype 1 of the endothelial protein C receptor gene on activated protein C levels.Semantic proximity Read ↗

Hyperprothrombinaemia-induced APC resistance: differential influence on fibrin formation and fibrinolysis.Semantic proximity Read ↗

Basic residues in the 37-loop of activated protein C modulate inhibition by protein C inhibitor but not by alpha(1)-antitrypsin.Semantic proximity Read ↗

The Endothelium Modulates the Prothrombotic Phenotype of Factor V Leiden: Evidence from an Ex Vivo ModelSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.