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Article

Low level of circulating activated protein C is a risk factor for venous thromboembolism.

Thrombosis and haemostasis - 1 Dec 2001

España F, Vayá A, Mira Y, Medina P, Estellés A, Villa P, Falcó C, Aznar J

Abstract excerpt

The levels of circulating activated protein C (APC) reflect in vivo protein C activation. The aim of this study was to determine whether a low APC level is an independent risk factor for venous thromboembolism (VTE). We measured APC in 160 patients with a history of VTE and without recognized thrombophilic defects, and in 199 healthy individuals. The mean (+/- SD) APC level was lower in patients (0.99 +/- 0.44...

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Identifiers

PMID: 11776301

Genes

APC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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