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Article

Vitamin K epoxide reductase genetic polymorphism is associated with venous thromboembolism: results from the EDITH Study.

Journal of thrombosis and haemostasis : JTH - 1 Oct 2007

Lacut K, Larramendy-Gozalo C, Le Gal G, Duchemin J, Mercier B, Gourhant L, Mottier D, Becquemont L, Oger E, Verstuyft C

Abstract excerpt

BACKGROUND: The vitamin K epoxide reductase complex subunit 1 (VKORC1) recycles endogenous vitamin K, a cofactor for vitamin K-dependent coagulation factor synthesis. Common polymorphisms in VKORC1, the gene coding for VKORC1, have been found to affect the dose response to vitamin K antagonists, and to confer an increased risk of vascular diseases in a Chinese population. The aim of this study was to evaluate the...

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Identifiers

PMID: 17883698
DOI: 10.1111/j.1538-7836.2007.02706.x

Genes

VKORC1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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