Article
Association between VKORC1 gene polymorphisms and ischemic cerebrovascular disease in Chinese Han population.
Journal of molecular neuroscience : MN - 1 Jun 2014
Zhang Hua, Yang Linyan, Feng Qingchuan, Fan Yujia, Zheng Hong, He Ying
Abstract excerpt
The vitamin K epoxide reductase subunit 1 gene (VKORC1) plays a key role in vitamin K recycling, and there is a close association between VKORC1 gene single-nucleotide polymorphisms (SNPs) and the required dose of warfarin, an anticoagulant. However, the association between VKORC1 SNPs and ischemic cerebrovascular disease (ICVD) has not been defined. This case-control study involved 370 patients with ICVD and 408...
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