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Article

Over-expression of cathepsin E and trefoil factor 1 in sessile serrated adenomas of the colorectum identified by gene expression analysis.

Virchows Archiv : an international journal of pathology - 1 Mar 2009

Caruso Maria, Moore James, Goodall Gregory J, Thomas Michelle, Phillis Stuart, Tyskin Anna, Cheetham Glenice, Lerda Nancy, Takahashi Hiroyuki, Ruszkiewicz Andrew

Abstract excerpt

Sessile serrated adenomas are now recognised as precursor lesions of a substantial subset of colorectal cancers arising via a so-called "serrated pathway". However, their biological markers remain to be defined. The aim of our study was to identify differentially expressed genes in sessile serrated adenomas and conventional adenomas. Gene expression analysis demonstrated molecular differences between polyp types....

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Source

Identifiers

PMID: 19172291
DOI: 10.1007/s00428-009-0731-0

Genes

BRAF
CTSE
KRAS
TFF1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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