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Article

Improved molecular classification of serrated lesions of the colon by immunohistochemical detection of BRAF V600E.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Jan 2014

Mesteri Ildiko, Bayer Günther, Meyer Jochen, Capper David, Schoppmann Sebastian F, von Deimling Andreas, Birner Peter

Abstract excerpt

BRAF V600E mutation in serrated lesions of the colon has been implicated as an important mutation and as a specific marker for the serrated carcinogenic pathway. Recent findings point to microvesicular hyperplastic polyps that have similar histologic and molecular features to sessile serrated adenomas/polyps, as potential colorectal carcinoma precursors. The aim of this study was to evaluate BRAF V600E mutation...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23887306
DOI: 10.1038/modpathol.2013.126

Genes

BRAF
KRAS

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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