Article
Immunohistochemical Examination is Highly Sensitive and Specific for Detection of the V600E BRAF Mutation in Colorectal Serrated Lesions.
Applied immunohistochemistry & molecular morphology : AIMM - 1 Jul 2021
Yamada Noriyuki, Eizuka Makoto, Sugimoto Ryo, Tanaka Yoshihito, Yanagawa Naoki, Yamano Hiroo, Suzuki Hiromu, Matsumoto Takayuki, Sugai Tamotsu
Abstract excerpt
Mutations in BRAF are important events in colorectal serrated lesions and specific genetic markers for the serrated pathway. However, examination of BRAF mutations is not easy in routine histopathologic analyses. Here, the authors examined 73 colorectal serrated lesions, including 21 hyperplastic polyps, 32 traditional serrated adenomas, and 30 sessile serrated lesions, for comparison of BRAF mutation status with...
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