Article
BRAF mutation is associated with the unique morphology of traditional serrated adenoma of the colorectum.
International journal of surgical pathology - 1 Oct 2013
Shi Yan, Li Juan, Wu Si-Yu, Qin Ling, Jiao Yu-Fei
Abstract excerpt
Traditional serrated adenoma (TSA) consists of glands with tall cells and short cells. Two kinds of cells alternate to give a unique serrated configuration. The aim of this study was to identify the relationship between the alterations of both Wnt and serrated pathways and the unique morphology of TSAs. The tall and short cells in 28 TSAs were separated by microdissection. Semi-nested polymerase chain reaction...
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