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Article

Promoter-specific control of E. coli RNA polymerase by ppGpp and a general transcription factor.

Genes & development - 15 Jan 2009

Roberts Jeffrey W

Abstract excerpt

The stringent response of Escherichia coli reflects a global influence of the nucleotide ppGpp on gene expression in response to nutrient starvation. For critical elements of the response, the target of ppGpp is RNA polymerase, which can be either repressed or activated in a promoter-dependent way. A small protein, DksA, which binds in the secondary channel of RNA polymerase, possibly along with other general...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19171778
DOI: 10.1101/gad.1770509

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Promoter-specific control of E. coli RNA polymerase by ppGpp and a general transcription factor.PMID 19171778Read ↗

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