Article
Role of the coiled-coil tip of Escherichia coli DksA in promoter control.
Journal of molecular biology - 2 Mar 2012
Lee Jeong-Hyun, Lennon Christopher W, Ross Wilma, Gourse Richard L
Abstract excerpt
Escherichia coli DksA works in conjunction with the small-molecule ppGpp to regulate transcription initiation negatively or positively, depending on the identity of the promoter. DksA is in a class of transcription factors that do not bind directly to DNA such as classical repressors or activators but rather bind in the RNA polymerase (RNAP) secondary channel such as the transcription elongation factors GreA and...
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