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Article

Super DksAs: substitutions in DksA enhancing its effects on transcription initiation.

The EMBO journal - 17 Jun 2009

Blankschien Matthew D, Lee Jeong-Hyun, Grace Elicia D, Lennon Christopher W, Halliday Jennifer A, Ross Wilma, Gourse Richard L, Herman Christophe

Abstract excerpt

At specific times during bacterial growth, the transcription factor DksA and the unusual nucleotide regulator ppGpp work synergistically to inhibit some Escherichia coli promoters (e.g. rRNA promoters) and to stimulate others (e.g. promoters for amino-acid synthesis and transport). However, the mechanism of DksA action remains uncertain, in part because DksA does not function like conventional transcription...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19424178
DOI: 10.1038/emboj.2009.126
PMCID: PMC2699356

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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