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Article

Unique clinical features and transcriptomic profiling of carcinogenesis in patients with familial lung cancer in Yunnan Province, Wumeng mountains, China.

Respiratory research - 10 Feb 2026

Zeng Jingtong, Lin Hongli, Shi Difang, Li Pengyu, Zhang Jinping, Yang Hao, Ming Chao, Huang Yunchao, Chen Ying

Abstract excerpt

BACKGROUND: Inherited genomic susceptibility and associated transcriptomic patterns are crucial players in lung cancer etiology. Lung cancer susceptibility is getting rising attention in carcinogenesis. The present study aimed to investigate unique clinical features and transcriptomic profile in patients with familial lung cancer (FLC) in Yunnan-Guizhou Plateau, Wumeng-Mountain area of China. METHODS: 1,823 local...

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Identifiers

PMID: 41664054
DOI: 10.1186/s12931-026-03503-x
PMCID: PMC12990475

Genes

MUC16
CD4

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