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Article

Ethnic differences in the association of SERPING1 with age-related macular degeneration and polypoidal choroidal vasculopathy.

Scientific reports - 24 Mar 2015

Liu Ke, Lai Timothy Y Y, Ma Li, Lai Frank H P, Young Alvin L, Brelen Marten E, Tam Pancy O S, Pang Chi Pui, Chen Li Jia

Abstract excerpt

Neovascular age-related macular degeneration (AMD) and polypoidal choroidal vasculopathy (PCV) are leading causes of irreversible blindness in developed countries. In this study, we investigated the association of single nucleotide polymorphisms (SNPs) in the serpin peptidase inhibitor, clade G, member 1 (SERPING1) gene with neovascular AMD and PCV. Two haplotype-tagging SNPs, rs1005510 and rs11603020, of...

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Source

Open in PubMed Open full text

Identifiers

PMID: 25800435
DOI: 10.1038/srep09424
PMCID: PMC4371106

Genes

SERPING1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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