Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

ARMS2 increases the risk of early and late age-related macular degeneration in the European Eye Study.

Ophthalmology - 1 Feb 2013

Chakravarthy Usha, McKay Gareth J, de Jong Paulus T V M, Rahu Mati, Seland Johan, Soubrane Gisele, Tomazzoli Laura, Topouzis Fotis, Vingerling Johannes R, Vioque Jesus, Young Ian S, Sofat Reecha, Hingorani Aroon D, Fletcher Astrid E

Abstract excerpt

OBJECTIVE: To study associations between severity stages of early and late age-related macular degeneration (AMD) and genetic variations in age-related maculopathy susceptibility 2 (ARMS2) and complement factor H (CFH) and to investigate potential interactions between smoking and ARMS2. DESIGN: Population-based, cross-sectional European Eye Study in 7 countries in Europe. PARTICIPANTS: Four thousand seven hundred...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cross-Sectional Studies
Share to Complement Factor H

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Europe

Share to Gene-Environment Interaction

Share to Genotyping Techniques

Share to Macular Degeneration

Share to Smoking

Share to Surveys and Questionnaires

Source

Identifiers

PMID: 23098369
DOI: 10.1016/j.ophtha.2012.08.004

Genes

ARMS2
CFH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

ARMS2 increases the risk of early and late age-related macular degeneration in the European Eye Study.PMID 23098369Read ↗

Polymorphisms in ARMS2/HTRA1 and complement genes and age-related macular degeneration in India: findings from the INDEYE study.Semantic proximity Read ↗

Risk alleles in CFH and ARMS2 and the long-term natural history of age-related macular degeneration: the Beaver Dam Eye Study.Semantic proximity Read ↗

Susceptibility genes and progression in age-related maculopathy: a study of single eyes.Semantic proximity Read ↗

Genetics of Unilateral and Bilateral Age-Related Macular Degeneration Severity Stages.Semantic proximity Read ↗

Extramacular drusen are highly associated with age-related macular degeneration, but not with CFH and ARMS2 genotypes.Semantic proximity Read ↗

Genetic and environmental risk factors for age-related macular degeneration in persons 90 years and older.Semantic proximity Read ↗

Cigarette smoking and the natural history of age-related macular degeneration: the Beaver Dam Eye Study.Semantic proximity Read ↗

Variations in five genes and the severity of age-related macular degeneration: results from the Muenster aging and retina study.Semantic proximity Read ↗

[Etiology and pathogenesis of age-related macular degeneration].Semantic proximity Read ↗

Association analysis of CFH and ARMS2 gene polymorphisms in a Brazilian cohort with age-related macular degeneration.Semantic proximity Read ↗

Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis.Semantic proximity Read ↗

The contribution of genetic factors to phenotype and progression of drusen in early age-related macular degeneration.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.