Article
No association of age-related maculopathy susceptibility protein 2/HtrA serine peptidase 1 or complement factor H polymorphisms with early age-related maculopathy in a Chinese cohort.
Molecular vision - 1 Jan 2013
Chen Jian-Huan, Yang Yunli, Zheng Yuqian, Qiu Minghui, Xie Mingliang, Lin Wenjie, Zhang Mingzhi, Pang Chi Pui, Chen Haoyu
Abstract excerpt
PURPOSE: Single nucleotide polymorphisms (SNPs) of age-related maculopathy susceptibility protein 2/HtrA serine peptidase 1 (ARMS2/HTRA1) and complement factor H (CFH) have been reported to be associated with age-related macular degeneration (AMD). The purpose of this study was to investigate the association of ARMS2/HTRA1 and CFH SNPs with early age-related maculopathy (ARM) in a Han Chinese cohort. METHODS: The...
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