Article
Influence of a self-assembling peptide, RADA16, compared with collagen I and Matrigel on the malignant phenotype of human breast-cancer cells in 3D cultures and in vivo.
Macromolecular bioscience - 13 May 2009
Mi Kun, Wang Guixia, Liu Zijia, Feng Zhihua, Huang Ben, Zhao Xiaojun
Abstract excerpt
Cancer-cell phenotype is not only the result of malignant progression, but also dependent on the microenvironment surrounding them, including influences from the extracellular matrix and its structural properties. We have investigated the influence of the nanofiber matrix of the self-assembling peptide, RADA16, in comparison with collagen I and Matrigel on the malignant phenotype of the human breast-cancer cell,...
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