Article
Axon regeneration requires a conserved MAP kinase pathway.
Science (New York, N.Y.) - 6 Feb 2009
Hammarlund Marc, Nix Paola, Hauth Linda, Jorgensen Erik M, Bastiani Michael
Abstract excerpt
Regeneration of injured neurons can restore function, but most neurons regenerate poorly or not at all. The failure to regenerate in some cases is due to a lack of activation of cell-intrinsic regeneration pathways. These pathways might be targeted for the development of therapies that can restore neuron function after injury or disease. Here, we show that the DLK-1 mitogen-activated protein (MAP) kinase pathway...
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