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Article

Age-dependent autophagy induction after injury promotes axon regeneration by limiting NOTCH

10 Jan 2020

Abstract excerpt

Macroautophagy/autophagy is essential for maintaining cellular homeostasis through the degradation of organelles and proteins. It also has a prominent role in modulating aging. However, the role of autophagy in the neuronal response to axon injury and axon regeneration, particularly in the context of aging, remains largely unknown. Our candidate genetic screen for axon regeneration regulators has identified genes...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 31920157
DOI: 10.1080/15548627.2020.1713645

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