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Article

Effect of tryptophan hydroxylase-2 rs7305115 SNP on suicide attempts risk in major depression.

Behavioral and brain functions : BBF - 25 Aug 2010

Zhang Yuqi, Zhang Changsong, Yuan Guozhen, Yao Jianjun, Cheng Zaohuo, Liu Chaojun, Liu Qinghai, Wan Gairong, Shi Guizhi, Cheng Yiren, Ling Yang, Li Ke

Abstract excerpt

BACKGROUND: Suicide and major depressive disorders (MDD) are strongly associated, and genetic factors are responsible for at least part of the variability in suicide risk. We investigated whether variation at the tryptophan hydroxylase-2 (TPH2) gene rs7305115 SNP may predispose to suicide attempts in MDD. METHODS: We genotyped TPH2 gene rs7305115 SNP in 215 MDD patients with suicide and matched MDD patients...

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Source

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Identifiers

PMID: 20738857
DOI: 10.1186/1744-9081-6-49
PMCID: PMC2939585

Genes

TPH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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