Article
Heterochronic genes control cell cycle progress and developmental competence of C. elegans vulva precursor cells.
Cell - 8 Mar 1996
Euling S, Ambros V
Abstract excerpt
Heterochronic genes control the timing of vulval development in the C. elegans hermaphrodite. lin-14 or lin-28 loss-of-function mutations cause the vulval precursor cells (VPCs) to enter S phase and to divide one larval stage earlier than in the wild type. A precocious vulva is formed by essentia...
Topics
- Animals
- Caenorhabditis elegans
- Cell Differentiation
- Cell Division
- Cell Nucleus
- DNA, Helminth
- Female
- Gene Expression
- Genes, Helminth
- Genotype
- Hydroxyurea
- Mutation
- Phenotype