Article
Heterochronic genes control cell cycle progress and developmental competence of C. elegans vulva precursor cells.
Cell - 8 Mar 1996
Euling S, Ambros V
Abstract excerpt
Heterochronic genes control the timing of vulval development in the C. elegans hermaphrodite. lin-14 or lin-28 loss-of-function mutations cause the vulval precursor cells (VPCs) to enter S phase and to divide one larval stage earlier than in the wild type. A precocious vulva is formed by essentially normal cell lineage patterns, governed by the same intercellular signals as in the wild type. Mutations that...
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