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Article

Evidence of epistasis between the catechol-O-methyltransferase and aldehyde dehydrogenase 3B1 genes in paranoid schizophrenia.

Biological psychiatry - 15 Jun 2009

Wang Yan, Hu Ying, Fang Yue, Zhang Kerang, Yang Hong, Ma Jintang, Xu Qi, Shen Yan

Abstract excerpt

BACKGROUND: Schizophrenia is a common yet severe psychiatric condition characterized by complex genetic mechanism and diverse clinical presentations. Our previous study indicated that the combined effect of two intronic single nucleotide polymorphisms (SNPs), which are located in the catechol-O-methyltransferase (COMT) and aldehyde dehydrogenase 3B1 (ALDH3B1) genes, respectively, conferred genetic risk to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Event-Related Potentials, P300

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Source

Identifiers

PMID: 19159868
DOI: 10.1016/j.biopsych.2008.11.027

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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