Article
Interaction between CYP19A1 polymorphisms and body mass index in the risk of endometrial cancer in postmenopausal Japanese women.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2011
Hosono Satoyo, Matsuo Keitaro, Ito Hidemi, Watanabe Miki, Hirose Kaoru, Nakanishi Toru, Tajima Kazuo, Tanaka Hideo
Abstract excerpt
Extra-ovarian sex hormone production plays an important role in endometrial cancer in postmenopausal women. Aromatase, which is encoded by CYP19A1, is a key enzyme in estrogen biosynthesis after menopause. To examine the association between polymorphisms in CYP19A1 and endometrial cancer risk among postmenopausal Japanese women, we conducted a hospital-based case control study in 48 patients with histologically...
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