Article
Genetic and environmental predictors, endogenous hormones and growth factors, and risk of estrogen receptor-positive breast cancer in Japanese women.
Cancer science - 1 Nov 2011
Yoshimoto Nobuyasu, Nishiyama Takeshi, Toyama Tatsuya, Takahashi Satoru, Shiraki Norio, Sugiura Hiroshi, Endo Yumi, Iwasa Mai, Fujii Yoshitaka, Yamashita Hiroko
Abstract excerpt
The incidence of breast cancer in Japanese women has doubled in all age groups over the past two decades. We have recently shown that this marked increase is mostly due to an increase in the estrogen receptor (ER)-positive subtype. It is necessary to establish risk factors capable of predicting the risk of ER-positive breast cancer that will enable the efficient selection of candidates for preventive therapy. We...
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