Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Aromatase gene (CYP 19) polymorphisms and endogenous androgen concentrations in a multiracial/multiethnic, multisite study of women at midlife.

The American journal of medicine - 1 Sept 2006

Sowers MaryFran R, Wilson Angela L, Kardia Sharon R, Chu Jian, Ferrell Robert

Abstract excerpt

A limited number of studies have focused on androgens in women's health, particularly at the genetic level. We evaluated testosterone and estradiol (E2) levels among women in relation to 5 single nucleotide polymorphisms (SNPs) of the aromatase (CYP 19) gene, the cytochrome P450 enzyme that converts androgens to estrogens. We related 5 aromatase SNPs (CYP 19 rs2414096, CYP 19 rs936306, CYP 19 rs2446405, CYP 19...

Topics

Adult
Androgens
Aromatase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Estradiol

Female

Humans

Middle Aged

Polymorphism, Single Nucleotide

Racial Groups

Sex Hormone-Binding Globulin

Testosterone

Source

Identifiers

PMID: 16949385
DOI: 10.1016/j.amjmed.2006.07.003

Genes

SHBG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Aromatase gene (CYP 19) polymorphisms and endogenous androgen concentrations in a multiracial/multiethnic, multisite study of women at midlife.PMID 16949385Read ↗

Association between CYP19A1 polymorphisms and sex hormones in postmenopausal Japanese women.Semantic proximity Read ↗

Sex steroid hormone gene polymorphisms and depressive symptoms in women at midlife.Semantic proximity Read ↗

The association of genetic polymorphisms in sex hormone biosynthesis and action with insulin sensitivity and diabetes mellitus in women at midlife.Semantic proximity Read ↗

Haplotype structures and functional polymorphic variants of the drug target enzyme aromatase (CYP19A1) in South Indian population.Semantic proximity Read ↗

Polymorphisms in CYP19A1, HSD17B1 and HSD17B2 genes and serum sex hormone level among postmenopausal Japanese women.Semantic proximity Read ↗

Sex steroid hormone pathway genes and health-related measures in women of 4 races/ethnicities: the Study of Women's Health Across the Nation (SWAN).Semantic proximity Read ↗

Variation in estrogen-related genes associated with cardiovascular phenotypes and circulating estradiol, testosterone, and dehydroepiandrosterone sulfate levels.Semantic proximity Read ↗

Association of genetic polymorphisms in CYP19A1 and blood levels of sex hormones among postmenopausal Chinese women.Semantic proximity Read ↗

Human aromatase: gene resequencing and functional genomics.Semantic proximity Read ↗

Association of genetic variations in aromatase gene with serum estrogen and estrogen/testosterone ratio in Chinese elderly men.Semantic proximity Read ↗

Associations between CYP19A1 polymorphisms, Native American ancestry, and breast cancer risk and mortality: the Breast Cancer Health Disparities Study.Semantic proximity Read ↗

<i>CYP19</i> (aromatase) haplotypes and endometrial cancer riskSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.