Article
Association of genetic variations in aromatase gene with serum estrogen and estrogen/testosterone ratio in Chinese elderly men.
Clinica chimica acta; international journal of clinical chemistry - 1 Jan 2010
Jiang Jieying, Tang Nelson L S, Ohlsson C, Eriksson Anna L, Vandenput Liesbeth, Chan Frank W K, Ching Jasmine K L, Kwok Anthony, Orwoll Eric, Kwok Timothy C Y, Woo Jean, Leung Ping Chung
Abstract excerpt
BACKGROUND: Single nucleotide polymorphism (SNP) rs2470152 of the gene CYP19A1 is associated with serum estradiol (E2) levels in Caucasian men. However, it remains to be verified if rs2470152 is the sole determinant accounting for the association. We determined whether 2 CYP19A1 SNPs tagging different haploblocks (rs2470152 and rs2899470) are associated with sex steroid levels in Chinese men. METHOD: Serum sex...
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