Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of X-box binding protein 1 ( XBP1) genotype with morning cortisol and 1-year clinical course after a major depressive episode.

The international journal of neuropsychopharmacology - 1 Mar 2009

Grunebaum Michael F, Galfalvy Hanga C, Huang Yung-yu, Cooper Thomas B, Burke Ainsley K, Agnello Melissa, Oquendo Maria A, Mann J John

Abstract excerpt

Brain diseases including Alzheimer's and Parkinson's involve the cellular 'unfolded protein' (UPR) stress response. Psychiatric illnesses such as depressive disorders are thought to involve brain stress-response pathways. The XBP1 gene encodes a key transcription factor in the UPR stress response and therefore could be involved in the pathophysiology of depressive disorders. A functional polymorphism (-116C-->G)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Circadian Rhythm
Share to Depressive Disorder, Major

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hydrocortisone

Share to Radioimmunoassay

Share to Regulatory Factor X Transcription Factors

Share to Statistics, Nonparametric

Share to Survival Analysis

Share to X-Box Binding Protein 1

Source

Open in PubMed Open full text

Identifiers

PMID: 19154631
DOI: 10.1017/S1461145708009863
PMCID: PMC3773868

Genes

XBP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of X-box binding protein 1 ( XBP1) genotype with morning cortisol and 1-year clinical course after a major depressive episode.PMID 19154631Read ↗

Impaired feedback regulation of XBP1 as a genetic risk factor for bipolar disorder.Semantic proximity Read ↗

The -116C/G polymorphism in XBP1 gene is associated with psychiatric illness in Asian population: A meta-analysis.Semantic proximity Read ↗

X-box binding protein 1 (XBP1) C--116G polymorphisms in bipolar disorders and age of onset.Semantic proximity Read ↗

A possible association between the -116C/G single nucleotide polymorphism of the XBP1 gene and lithium prophylaxis in bipolar disorder.Semantic proximity Read ↗

Polymorphism -116C/G of human X-box-binding protein 1 promoter is associated with risk of Alzheimer's disease.Semantic proximity Read ↗

Regulation of Memory Formation by the Transcription Factor XBP1Semantic proximity Read ↗

Lack of association between XBP1 genotype and calcium signaling in the platelets of healthy subjects.Semantic proximity Read ↗

Association of the XBP1-116C/G polymorphism with schizophrenia in the Japanese population.Semantic proximity Read ↗

Impaired endoplasmic reticulum stress response in B-lymphoblasts from patients with bipolar-I disorder.Semantic proximity Read ↗

A case–control study provides evidence of association for a functional polymorphism −197C/G in XBP1 to schizophrenia and suggests a sex-dependent effectSemantic proximity Read ↗

Association study of a functional promoter polymorphism in the XBP1 gene and schizophrenia.Semantic proximity Read ↗

Relationship between XBP1 genotype and personality traits assessed by TCI and NEO-FFI.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.