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Article

Impaired endoplasmic reticulum stress response in B-lymphoblasts from patients with bipolar-I disorder.

Biological psychiatry - 15 Jul 2007

So Jonathan, Warsh Jerry J, Li Peter P

Abstract excerpt

BACKGROUND: Aberrant intracellular calcium (Ca2+) signaling in patients with bipolar-I disorder (BD-I) suggests disturbed endoplasmic reticulum (ER) function in BD. We examined whether the ER stress response is altered in BD-I patients and the relationship to basal intracellular Ca2+ levels ([Ca2+]B), in B lymphoblasts (BLCLs) from BD-I patients. METHODS: Endoplasmic reticulum stress-induced X-box binding protein...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17217928
DOI: 10.1016/j.biopsych.2006.10.014

Genes

XBP1
EBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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