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Article

Structure of a highly stable mutant of human fibroblast growth factor 1.

Acta crystallographica. Section D, Biological crystallography - 1 Jan 2009

Szlachcic Anna, Zakrzewska Małgorzata, Krowarsch Daniel, Os Vibeke, Helland Ronny, Smalås Arne O, Otlewski Jacek

Abstract excerpt

Fibroblast growth factors (FGFs) are involved in diverse cellular processes such as cell migration, angiogenesis, osteogenesis, wound healing and embryonic and foetal development. Human acidic fibroblast growth factor (FGF-1) is the only member of the FGF family that binds with high affinity to all four FGF receptors and thus is considered to be the human mitogen with the broadest specificity. However,...

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Identifiers

PMID: 19153468
DOI: 10.1107/S0907444908039486

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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