Article
Mitochondrial DNA haplogroups confer differences in risk for age-related macular degeneration: a case control study.
BMC medical genetics - 9 Jan 2013
Kenney M Cristina, Hertzog Dieter, Chak Garrick, Atilano Shari R, Khatibi Nikan, Soe Kyaw, Nobe Andrew, Yang Elizabeth, Chwa Marilyn, Zhu Feilin, Memarzadeh Masood, King Jacqueline, Langberg Jonathan, Small Kent, Nesburn Anthony B, Boyer David S, Udar Nitin
Abstract excerpt
BACKGROUND: Age-related macular degeneration (AMD) is the leading cause of vision loss in elderly, Caucasian populations. There is strong evidence that mitochondrial dysfunction and oxidative stress play a role in the cell death found in AMD retinas. The purpose of this study was to examine the association of the Caucasian mitochondrial JTU haplogroup cluster with AMD. We also assessed for gender bias and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.