Article
Population variability of the FimH type 1 fimbrial adhesin in Klebsiella pneumoniae.
Journal of bacteriology - 1 Mar 2009
Stahlhut Steen G, Chattopadhyay Sujay, Struve Carsten, Weissman Scott J, Aprikian Pavel, Libby Stephen J, Fang Ferric C, Krogfelt Karen Angeliki, Sokurenko Evgeni V
Abstract excerpt
FimH is an adhesive subunit of type 1 fimbriae expressed by different enterobacterial species. The enteric bacterium Klebsiella pneumoniae is an environmental organism that is also a frequent cause of sepsis, urinary tract infection (UTI), and liver abscess. Type 1 fimbriae have been shown to be critical for the ability of K. pneumoniae to cause UTI in a murine model. We show here that the K. pneumoniae fimH gene...
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