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Article

Clonal analysis reveals high rate of structural mutations in fimbrial adhesins of extraintestinal pathogenic Escherichia coli.

Molecular microbiology - 1 Feb 2006

Weissman Scott J, Chattopadhyay Sujay, Aprikian Pavel, Obata-Yasuoka Mana, Yarova-Yarovaya Yuliya, Stapleton Ann, Ba-Thein William, Dykhuizen Daniel, Johnson James R, Sokurenko Evgeni V

Abstract excerpt

Type 1 fimbriae of Escherichia coli mediate mannose-specific adhesion to host epithelial surfaces and consist of a major, antigenically variable pilin subunit, FimA, and a minor, structurally conserved adhesive subunit, FimH, located on the fimbrial tip. We have analysed the variability of fimA and fimH in strains of vaginal and other origin that belong to one of the most prominent clonal groups of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 16420365
DOI: 10.1111/j.1365-2958.2005.04985.x
PMCID: PMC1380272

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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