Article
A variable region within the genome of Streptococcus pneumoniae contributes to strain-strain variation in virulence.
PloS one - 5 May 2011
Harvey Richard M, Stroeher Uwe H, Ogunniyi Abiodun D, Smith-Vaughan Heidi C, Leach Amanda J, Paton James C
Abstract excerpt
The bacterial factors responsible for the variation in invasive potential between different clones and serotypes of Streptococcus pneumoniae are largely unknown. Therefore, the isolation of rare serotype 1 carriage strains in Indigenous Australian communities provided a unique opportunity to compare the genomes of non-invasive and invasive isolates of the same serotype in order to identify such factors. The human...
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