Article
DNA adenine methylation modulates pathogenicity of Klebsiella pneumoniae genotype K1.
Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi - 1 Aug 2017
Fang Chi-Tai, Yi Wen-Ching, Shun Chia-Tung, Tsai Shih-Feng
Abstract excerpt
BACKGROUND/PURPOSE: Klebsiella pneumoniae genotype K1 is a highly virulent pathogen that causes liver abscess and metastatic endophthalmitis/meningitis. Whether its pathogenicity is controlled by DNA adenine methylase (Dam), an epigenetic regulator of bacterial virulence gene expression, is yet unknown. We aimed to study the role of DNA adenine methylation in the pathogenicity of K. pneumoniae genotype K1....
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