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Article

NAD in Skin: Therapeutic Approaches for Niacin

1 Jan 2009

Abstract excerpt

The maintenance and regulation of cellular NAD(P)(H) content and its influence on cell function involves many metabolic pathways, some of which remain poorly understood. Niacin deficiency in humans, which leads to low NAD status, causes sun sensitivity in skin, indicative of deficiencies in responding to UV damage. Animal models of niacin deficiency demonstrate genomic instability and increased cancer development...

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PMID: 19149600
DOI: 10.2174/138161209787185760

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