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Article

agr receptor mutants reveal distinct modes of inhibition by staphylococcal autoinducing peptides.

Proceedings of the National Academy of Sciences of the United States of America - 27 Jan 2009

Geisinger Edward, Muir Tom W, Novick Richard P

Abstract excerpt

Through the agr quorum-sensing system, staphylococci secrete unique autoinducing peptides (AIPs) and detect their concentration via the AgrC transmembrane receptor, coordinating local bacterial population density with global changes in gene expression. Unique AIP and AgrC variants exist within and between species, and although autologous interactions lead to agr activation, heterologous interactions usually lead...

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Source

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Identifiers

PMID: 19147840
DOI: 10.1073/pnas.0807760106
PMCID: PMC2633565

Genes

AIP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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