Article

Single-cell approach dissecting <i>agr</i> quorum sensing dynamics in <i>Staphylococcus aureus</i>

2024-02-27

Abstract excerpt

Staphylococcus aureus both colonizes humans and causes severe virulent infections. Virulence is regulated by the agr quorum sensing system and its autoinducing peptide (AIP), with dynamics at the single-cell level across four agr -types – each defined by distinct AIP sequences and capable of cross-inhibition – remaining elusive. Employing microfluidics, time-lapse microscopy, and deep-learning image analysis, we...

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Literature Corpus work: df48dc3a-6250-555c-9c20-12a56dcefefd
DOI: 10.1101/2024.02.27.582246

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