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Article

Frequent genomic abnormalities in acute myeloid leukemia/myelodysplastic syndrome with normal karyotype.

Haematologica - 1 Feb 2009

Akagi Tadayuki, Ogawa Seishi, Dugas Martin, Kawamata Norihiko, Yamamoto Go, Nannya Yasuhito, Sanada Masashi, Miller Carl W, Yung Amanda, Schnittger Susanne, Haferlach Torsten, Haferlach Claudia, Koeffler H Phillip

Abstract excerpt

BACKGROUND: Acute myeloid leukemia is a clonal hematopoietic malignant disease; about 45-50% of cases do not have detectable chromosomal abnormalities. Here, we identified hidden genomic alterations and novel disease-related regions in normal karyotype acute myeloid leukemia/myelodysplastic syndrome samples. DESIGN AND METHODS: Thirty-eight normal karyotype acute myeloid leukemia/myelodysplastic syndrome samples...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19144660
DOI: 10.3324/haematol.13024
PMCID: PMC2635399

Genes

ETV6
FLT3
JAK2
RUNX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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