Detection of copy number alterations in acute myeloid leukemia and myelodysplastic syndromes.

Abstract excerpt

Chromosomal deletions and amplifications that occur in affected cells from patients with myelodysplastic syndromes and acute myeloid leukemia often contain genes that contribute to disease pathogenesis. Identification of copy number alterations (deletions and amplifications) and regions of copy neutral loss of heterozygosity using array-based platforms has led to the identification of genes that are commonly...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Comparative Genomic Hybridization
• Share to DNA Copy Number Variations