Article
A rapid method for detection of five known mutations associated with aminoglycoside-induced deafness.
BMC medical genetics - 13 Jan 2009
Bardien Soraya, Human Hannique, Harris Tashneem, Hefke Gwynneth, Veikondis Rene, Schaaf H Simon, van der Merwe Lize, Greinwald John H, Fagan Johan, de Jong Greetje
Abstract excerpt
BACKGROUND: South Africa has one of the highest incidences of multidrug-resistant tuberculosis (MDR-TB) in the world. Concomitantly, aminoglycosides are commonly used in this country as a treatment against MDR-TB. To date, at least five mutations are known to confer susceptibility to aminoglycosi...
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