Article
Evaluation of the contribution of cyclooxygenase 2 genotypes to breast cancer in Taiwan.
Anticancer research - 1 Nov 2014
Su Chen-Hsien, Hsiao Chieh-Lun, Chang Wen-Shin, Liu Liang-Chih, Wang Hwei-Chung, Tsai Chia-Wen, Li Long-Yuan, Tsai Chang-Hai, Bau Da-Tian
Abstract excerpt
Overexpression of cyclooxygenase 2 (COX-2) has been suggested to be associated with breast carcinogenesis. The aim of the present study was to evaluate the contribution of genotypic polymorphisms in COX-2 to breast cancer risk of Taiwanese females. In total, 1,232 breast cancer patients and 1,232 healthy controls were genotyped by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP)...
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