Article
Insensitivity to the cytolytic effects of glucocorticoids in vivo is associated with a novel "slow death" phenotype.
Cancer research - 15 Oct 1991
Thompson E A
Abstract excerpt
Tumors formed from wild type P1798 mouse lymphoma cells undergo regression when treated with pharmacological doses of natural and synthetic glucocorticoids in vivo. Variants have been selected that are insensitive to the cytolytic effects of glucocorticoids in vivo. Although the response of wild type and insensitive tumors is markedly different in vivo, the manner in which cells from such tumors respond to...
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