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Article

Cytotoxic T lymphocytes and glucocorticoids activate an endogenous suicide process in target cells.

Nature - 1 Jan 2000

Ucker D S

Abstract excerpt

Cytotoxic T lymphocytes (CTL) induce a cytolytic process in target cells which, like the glucocorticoid-mediated cytolysis of immature thymocytes, effects a rapid and characteristic degradation of chromosomal DNA. I have explored the possibility that these two lethal processes share a common pathway by studying the susceptibility of glucocorticoid-resistant mutants to CTL-mediated killing. Here, I report that an...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 3494953
DOI: 10.1038/327062a0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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