Article
Glucocorticoid insensitivity of P1798 lymphoma cells is associated with production of a factor that attenuates the lytic response.
Cancer research - 15 Oct 1991
Thompson E A
Abstract excerpt
P1798 murine lymphoma cells die when exposed to glucocorticoids in vivo. Such cells are sensitive to glucocorticoids in culture in serum-free medium, and 80-90% of wild type cells will die within 24 h after addition of 0.1 microM dexamethasone. However, addition of fetal bovine serum prevents cell death in culture. Variants that were selected for resistance to the cytolytic effects of glucocorticoids in vivo are...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
