Glucocorticoid insensitivity of P1798 lymphoma cells is associated with production of a factor that attenuates the lytic response.

Article

Glucocorticoid insensitivity of P1798 lymphoma cells is associated with production of a factor that attenuates the lytic response.

Cancer research - 15 Oct 1991

Thompson E A

Abstract excerpt

P1798 murine lymphoma cells die when exposed to glucocorticoids in vivo. Such cells are sensitive to glucocorticoids in culture in serum-free medium, and 80-90% of wild type cells will die within 24 h after addition of 0.1 microM dexamethasone. However, addition of fetal bovine serum prevents cel...

Topics

Cell Death
Culture Media
Dexamethasone
Drug Resistance
Glucocorticoids
Growth Substances
Lymphoma, Non-Hodgkin
Phenotype
Time Factors
Tumor Cells, Cultured

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