Article
Isolation and characterization of apoptosis-resistant mutants from a radiosensitive mouse lymphoma cell line.
Radiation research - 1 Jan 1998
Kawai H, Kitamura Y, Nikaido O, Tatsuka M, Hama-Inaba H, Muto M, Ohyama H, Suzuki F
Abstract excerpt
To analyze specific genes related to radiation-induced apoptosis, 12 apoptosis-resistant clones were isolated from cells of the radiosensitive mouse thymic lymphoma 3SB line after treatment with ethyl methanesulfonate. Five of 12 clonal cell lines were recloned and were examined for their suscept...
Topics
- Animals
- Apoptosis
- Genes, p53
- Lymphoma
- Mice
- Mutation
- Radiation Tolerance
- Tumor Cells, Cultured
- Tumor Suppressor Protein p53
- Ultraviolet Rays
- X-Rays