Article
Differential allelic expression of dopamine D1 receptor gene (DRD1) is modulated by microRNA miR-504.
Biological psychiatry - 15 Apr 2009
Huang Weihua, Li Ming D
Abstract excerpt
BACKGROUND: Previously, we reported that dopamine D1 receptor gene (DRD1) is associated with nicotine dependence (ND) and demonstrated that two alleles (A and G) of polymorphism rs686 in the 3'-untranslated region (3'UTR) of DRD1 are expressed differentially. However, the mechanism underlying the differential expression remains to be determined. We hypothesize that it is caused by miRNA targeting. METHODS: We...
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