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Article

Role of nicotine dependence in the association between the dopamine receptor gene DRD3 and major depressive disorder.

PloS one - 1 Jan 2014

Korhonen Tellervo, Loukola Anu, Wedenoja Juho, Nyman Emma, Latvala Antti, Broms Ulla, Häppölä Anja, Paunio Tiina, Schrage Andrew J, Vink Jaqueline M, Mbarek Hamdi, Boomsma Dorret I, Penninx Brenda W J H, Pergadia Michele L, Madden Pamela A F, Kaprio Jaakko

Abstract excerpt

BACKGROUND: The aims of this study were to analyze associations of dopamine receptor genes (DRD1-5) with Major Depressive Disorder (MDD) and nicotine dependence (ND), and to investigate whether ND moderates genetic influences on MDD. METHODS: The sample was ascertained from the Finnish Twin Cohor...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24927283
DOI: 10.1371/journal.pone.0098199
PMCID: PMC4057087

Genes

DRD3
DRD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24927283-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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